microCapStar End-tidal CO2 Monitor for Mice

Micro-sampling CO2 analyzer for mice

MicroCapStar

Product Category: Gas Analyzers

Part No.: 15-10000

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Data Sheet

Standard Features
Specifications
Overview

Fast Response
Accurate and stable monitoring
Ultra-low sample flow rate
Linear output voltage
End-tidal peak or continuous readings
Measures respiratory rate
For mice, rats, and larger animals

Carbon dioxide measurement: single beam, non-dispersive infrared
Measurement range: 0 - 9.9% (0 - 76.0mmHg) CO₂
Accuracy: 0.15% (1.1mmHg)
Resolution (internal and analog output): 0.01% (0.1mmHg)
Resolution (display): 0.1% (1.0mmHg)
Linearity: 0.1% CO₂
Repeatability: 0.1% CO₂
Response time (T10 - T90): 75mS at 70 ml/min through cell
Sample cell materials: sapphire and stainless steel
Analog output scaling: 0.5V/% (0-5V)
Response time (T10 - T90): 150mS at 50 ml/min sampling
Zero stability: 0.2% (8 hours), 0.3% (24 hours)
Interference effects: 50% N₂O: 0.1% at 0% CO₂, 0.6% at 5% CO₂ (uncomp.)
Maximum sample cell pressure: +5 psig
Interference effects: vaporized anaesthetic agents: negligible
Operating temperature range: 5-40° C
Optical bench temperature: 48° C, controlled
Warm-up time: 4 min to 0.2%, 10 min to 0.1%
ETCO2 trend display: 5 minute graphical scrolling display
Sample flow (sample inlet - carrier flow out): 10ml/min nominal, adjustable from 5.0 - 20ml/min
Sample tubing connections (carrier flow, sample inlet): Luer female
Calibration controls: Zero, Span
ETCO2 alarm adjustment range: 1.0 - 9.9% (8 - 75mmHg)
Respiratory rate measurement range: 5 - 200 breaths/min
Signal outputs (rear panel): BNC jacks
CO₂ output scaling: 0.5V / %CO₂
Respiratory rate output scaling: 0.025V / bpm
Alarm output: 5V if alarm condition, 0V if no alarm
Serial data output format: 2400 baud, 8 data, no parity, 1 stop bit
Electrical requirements: 120VAC/220VAC switchable, 35VA
Dimensions: 19W x 5.25H x 16D in., 49W x 13H x 41D cm
Weight: 10 lbs. (4.5kg)

The microCapStar End-Tidal Carbon Dioxide Analyzer provides accurate end-tidal or continuous measurement of expired CO₂ in animals as small as mice. It features very low sample flow requirements, rapid response time, and long-term stability. Respiratory rate (RR) is computed using the excursions of the CO₂ waveform. The CO₂ and RR measurements, as well as a trend plot of the end-tidal values, are displayed on the graphics LCD screen.

The heart of the microCapStar is a temperature-controlled infrared CO₂ sensor. Low sample flow and rapid response is achieved with a carrier gas system employing digitally-controlled active flow management. This technique automatically maintains the ratio of carrier flow to sample flow, which is essential for accurate measurements. The heated measurement cell prevents water condensation, even during long-term measurement sessions. The standard sample tubing set is 1m long, but lengths over 2.5m are possible.

The front-panel display shows CO₂ concentration (either instantaneous or ETCO2) in either percent or mmHg, and a 5-minute trend plot of ETCO2.. Calibration is performed with a single calibration gas and room air. An adjustable ETCO2 alarm provides a warning when end-tidal values fall out of a user-adjustable preset range. All adjustments are performed using a single knob. Built-in diagnostics monitoring warn of plugged sample tubing or other fault conditions.

The advanced features, reliability, and ease of operation of the microCapStar make it the perfect companion to our Small Animal Ventilators for monitoring respiratory status. With the AVS-1 Advanced Ventilator System, it can be used to control end-tidal CO₂. An accessory pack containing spare low-volume sample tubing and a variety of connectors and fittings is included with the instrument. A range of accessories is available to ensure easy setup and convenient operation.

CO₂ monitoring is widely recognized as an important measure of the respiratory status of experimental animals. It is useful in setting ventilator parameters, and serves to gauge depth of anesthesia in unassisted, spontaneously breathing animals as well. The microCapStar extends this important technique to the realm of small experimental animals.