Accurate oxygen consumption measurement for 1 - 8 small animals
MMX-2, MMX-8
- Oxygen analyzer type: paramagnetic
- Linearity (0 - 100%): +0.1% O2
- Repeatability: < 0.01% O2/hour
- Zero stability: +0.002% O2/hour
- Response time: 2.0 seconds
- Operating temperature: 0 - 65oC
- Maximum pressure: 15 psi
- Maximum sample flow: 250 ml/min
- Instrument measurement range: 0 - 24.5%
- O2 Carbon Dioxide analyzer type: single-beam infrared
- Operating range: 0 - 5000ppm (0.5%)
- CO2 Linearity (full scale): 1%
- FS Zero drift: 2%
- FS/week Sensor cell temperature: controlled at 60oC
- Warm-up time: <15 min
- Maximum sample flow: 200 ml/min
- Instrument measurement range: 0 - 0.41%CO2
- Flow transducer: thermal mass flowmeter
- Flow range: 0 - 10,000 ml/min
- Linear flow range: 50 - 10,000 ml/min
- Response time: < 2S
- Operating temperature: -20 - 70oC
- Main unit analog outputs: flow, O2, CO2
- Analog signal outputs (rear panel): BNC jacks
- Flow output: 1mV/ml/min
- Flow output zero offset: 1.250V
- O2 output: 0.1667V/%O2
- CO2 output: 10V/%CO2
- Serial data output format: 9600 baud, 8 data bits, no parity, 1 stop bit
- Serial data interval: complete set of readings sent 1 per minute
- Serial output connector (rear panel): DB9 female
- Dimensions, main unit: 19W x 5.25H x 15D in.
- Power requirements: 120/240V (switchable), 200VA
The MM-100 Metabolic Monitor System measures oxygen consumption (VO2) and CO2 production (VCO2) of small animals using the open circuit technique. The animal is placed in a closed chamber with a known flow of fresh air passing through it. Oxygen and carbon dioxide concentrations are measured at the inlet and outlet of the chamber. The three measurements (flow, O2, and CO2) enable the computation of oxygen consumption, CO2 production, and Respiratory Exchange Ratio (RER), or VCO2/VO2.
MMX-2 and MMX-8 MMX-Series Expanders allow the user to simultaneously monitor 2 or up to 8 animals with the MM-100 Metabolic Monitoring System.
Simple Set Up and Operation
The animal is placed in the provided chamber and allowed to equilibrate for 5 - 10 minutes. All gas and flow measurements, and computed results are shown on the front panel LCD display panel. A serial port connection sends the measurements to any attached computer. Using the included WindowsTM software, the readings for O2 consumption and CO2 production, along with their moving time averages, are plotted. Data can be logged to simple ASCII files for further analysis. Standardization against room air is automatically performed at intervals, so the accuracy of the system is maintained for long intervals of monitoring.
Front panel display panel shows all gas, flow, and computed measurements, as well as elapsed time and chamber being monitored.
Multiple Chamber Systems
Expansion to multiple animals is straightforward. Using the MMX-2 or MMX-8 (for two and eight animals, respectively) expansion units, gas sampling and measurement is automatically sequenced between the chambers. This results in an accurate, economical system for screening large numbers of animals for these important physiological parameters.
MM-COMM Monitoring Software
Each MM-100 system includes WindowsTM software for graphically displaying and logging the metabolic data. This software provides a Data Panel showing all the current raw and computed measurements. Data is logged in a simple ASCII format for directly importing it into a spreadsheet or other analysis program. Each record is tagged with the animal number and time of the measurement.
Complete Package
The MM-100 comes complete with all necessary components for a single-chamber measurement. This includes the main MM-100 unit, small animal chamber, air pump, drying tubes, and required tubing. The only consumable item is the Drierite material for drying the gas sample.
Accessories
Dessicant Bulk (Anhydrone)
Bulk Drierite dessicant, Anhydrone.
Mouse cage
Measurement chamber, acrylic, approximately 1 liter volume, 17.9 x 11.1 x 5.7cm
Suitable for mouse up to 50g, reusable
Related Products
MM-100 Metabolic Monitor
The MM-100 Metabolic Monitor is a complete system for measuring oxygen consumption in the small animal. Using the latest technology in paramagnetic O2, infrared CO2, and thermal mass flowmeter analyzers, it automatically computes O2 consumption, CO2 production, and respiratory exchange ratios (RER).