SAR-830/AP Small Animal Ventilator

• Dependable, all-electronic ventilator
• Pressure or volume-cycled operation
• Wide tidal volume and rate range
• Mice to Guinea pig size
• Expandable to 5 animals
• Safe with oxygen and anesthesia

• Respiratory rate range: 5 - 200 breaths/min
• Tidal Volume range (NOTE 1): 0.2 - 35ml
• Inspiration time range: 0 - 5.00 seconds
• Inspiratory flow range (NOTE 2): 100 - 1000 ml/minute
• Pressure control range: 0 - 50.0 cmH2O
• Analog rate output voltage: 10mV/breath/min
• Analog pressure output voltage: 50mV/cmH2O
• Logic Sync Out voltage: 5V (TTL)
• Remote-control inputs: two TTL logic inputs
• Power requirements: 120/240VAC, selectable
• Dimensions: 9Wx5.5Hx9D in (23x14x23 cm)

NOTE 1 Using internal valves External valve assemblies available for larger animals provide up to 100ml volumes.
NOTE 2 Rat - Guinea pig Mouse Kit provides special low range flowmeter and mouse-compatible tubing set.

To set up the SAR-830/AP, you first need to know the desired Tidal Volume (VT) and Respiratory Rate (RR). These can be determined from literature references, or from the charts at the back of our instruction manuals. Besides VT and RR, the other parameter you need is the Inspiration:Expiration Ratio, or IE. For rodents, this is often set as 40% (0.40), which allows for a slightly longer expiration phase. With these basic numbers in hand, the equations below will give the needed SAR-830/AP settings.  

First, determine Inspiratory Time (TI) in seconds:
TI = (IE X 60) / RR

Then, determine inspiratory Flow Rate in ml/min:
FLOW = (VT X 60) / TI

Note that VT is in ml, RR is in breaths/minute, TI is in seconds, and FLOW is in ml/minute. The equations account for the seconds & minutes automatically.

Here is an example for a 300g rat:
RR = 55 breaths/minute, VT = 2.5ml, and IE = 40% (0.40)

TI = (0.4 X 60) / 55 = 0.436s, and

FLOW = (2.5 X 60) / 0.436 = 344ml/min

On the SAR-830/AP ventilator, you would then dial in the RR directly using the RATE dial and the digital display. Adjust the flowmeter to the FLOW setting, and the INSP TIME dial for the TI setting. To adjust VT up or down from these settings, it is most convenient to simply increase or decrease the FLOW, while leaving the timing settings as is.